Below is the lecture schedule. All lectures are in 100 CNRB at 1:00 pm. The lecture topics and lecturer are subject to change, but the dates and times are set. Readings listed under each lecture should be read before lecture. Some readings are marked as optional, though you are encouraged to read all of the posted materials. The readings will be updated as the term progresses.
Scheduled office hours for the TAs to help you with your homework will be decided during the first week of class.
Assignment/due dates
- Homework 1 assigned Th 10/05, due Th 10/19
- Homework 2 assigned Th 10/19, due Th 11/02
- Homework 3 assigned Th 11/02, due Th 11/16
- Homework 4 assigned Tue 11/21, due Tue 12/05
- News and Views assigned Tues 09/26, due at 11:59 PM, Fri 12/08
All problem sets are submitted as Jupyter notebooks, and the News & Views article is submitted as a PDF. All are submitted via Canvas.
Lecture Schedule
- L1: Tu 09/26: Intro to Protein Engineering and notes (SLM)
- L2: Th 09/28: (NAP)
- L3: Tu 10/03: (NAP)
- L4: Th 10/05: (NAP)
- L5: Tu 10/10: (NAP)
- L6: Th 10/12: (NAP)
- L7: Tu 10/17: (NAP)
- L8: Th 10/19: (NAP)
- L9: Tu 10/24: (NAP)
- L10: Th 10/26: (NAP)
- L11: Tu 10/31: Neutrality and Intro to Directed Evolution and notes (SLM)
- L12: Th 11/02: Error-prone PCR and Site Saturation Mutagenesis and notes (SLM)
- L13: Tu 11/07: Recombination and notes (SLM)
- L14: Th 11/9: Screening and Selection, Protein Stability (SLM)
- L15: Tu 11/14: MM and MD (SLM)
- L16: Th 11/16: Bioscience Industry Day 12-3pm
- L17: Tu 11/21: Computational Protein Design (SLM)
- L18: Tu 11/28: Homology and PyMOL Tutorial (ZAM/NJF)
- L19: Th 11/30: Protein Folding and notes (SLM)
Sequences and Structures from lecture that you can play around with on NUPACK.